PUBLICATIONS

Through its publications, INSS provides rigorous, forward‑looking research and analysis on critical national security issues that support the joint warfighter and inform Department of War decision‑makers.

 

Publications

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Tag: biodefense

Research and developement concept background of scientist or reseacher using microscope in biotechnology laboratory overlay with DNA strand and molecules symbol, concept of DNA engineering.

March 31, 2026

Defining the Palette of Biodeterrence: Appreciating a Broader Toolkit

As noted in the recently released Biodeterrence Framework, biological weapons present a uniquely complex challenge to traditional models of deterrence, in that their development can be concealed within ostensibly legitimate scientific enterprise, their effects may be delayed or ambiguous, and their attribution can often be difficult, particularly given the increasingly broadened scope of biothreat possibilities.

INSS Center for Strategic Deterrence and WMD Studies employees stand in front of the Framework for Biological Weapons Deterrence: Report Rollout event at National Defense University.

March 19, 2026

A Framework for Biological Weapons Deterrence Rollout Event

On 12 March, the Defense Threat Reduction Agency (DTRA) and the National Defense University (NDU) co-hosted the Framework for Biological Weapons Deterrence: Report Rollout event.

Biohazard symbol inside a high-containment lab

March 17, 2026

Biodeterrence in an Era of Convergent Threats

A recent report reveals that the Peoples’ Republic of China (PRC) has increasing focus upon and fiscal dedication to biosciences and biotechnology, with an estimated economic commitment of 5-8% of its total national research and development spending, amounting to approximately $32 billion in comparable USD in annual funding.

Cover of a report titled “A Framework for Biological Weapons Deterrence.” The design features blue circular graphics with the word “UNCLASSIFIED” at the top and bottom. The subtitle reads: Center for the Study of Weapons of Mass Destruction, Institute for National Strategic Studies, National Defense University, August 2025. Two photos appear on the cover: one shows emergency responders wearing bright yellow hazmat suits standing near a fire truck; the other shows a U.S. Army soldier in uniform examining a sample through a laboratory microscope. A disclaimer notes that the views expressed are those of the authors and not official U.S. government policy. Logos for the Defense Threat Reduction Agency, National Defense University, and the Institute for National Strategic Studies appear at the bottom.

March 16, 2026

A Framework for Biological Weapons Deterrence

The United States and its allies and partners face a rapidly expanding array of biothreats, to include the potential employment of increasingly sophisticated and lethal biological weapons (BW).

Dictyostelium amoebae on a glass surface, immunoprobed with antiactin (green) and antibody against fucose-O-serine-containing peptides (red) and counterstained with DAPI (blue) for nuclei. (Copyright © 2025 Tiwari et al.

June 5, 2025

Dual use and gain-of-function research: a significant endeavor with biosecurity imperatives

Drs. Diane DiEuliis and James Giordano published a new paper entitled “Dual use and gain-of-function research: a significant endeavor with biosecurity imperatives,” in the international, peer-reviewed journal mSphere.

CSWMD

July 23, 2019

Systems-based Approach to Biodefense Policy Analysis

In this article, co-authored by Dr. Diane DiEuliis, the authors describe a systems-based analysis of the US biosecurity and biodefense policy landscape to analyze functional relationships between policies. They identify two approaches in US policy for countering biological threats: prevention of theft, diversion, or deliberate malicious use of biological technologies, and development of capabilities and knowledge to assess, detect, monitor, respond to, and attribute biological threats.

CSWMD

June 25, 2018

Roadmap for Implementing Biosecurity and Biodefense Policy in the United States

This past year, Dr. Diane DiEuliis, in partnership with Gryphon Scientific and Parsons, undertook an ambitious, systems-based analysis of biosecurity and biodefense policy in the United States. Here you can find the full report, an executive summary of the report, and the resultant Roadmap for U.S biodefense policy.

Toward a National Biodefense Strategy

April 1, 2003

Toward a National Biodefense Strategy

The United States is re-learning an important lesson in the first decade of the 21st century: adversaries may attack the United States, its interests, or those of friends and allies with biological weapons (BW).